The T-SPOT®.TB test is a single-visit blood test use to screen for tuberculosis (TB) infection. Also known as an interferon gamma release assay (IGRA), it uses Oxford Immunotec’s unique ELISpot technology to ensure the highest accuracy across patient groups. The T-SPOT.TB test is the only TB test with specificity of 98.8% and sensitivity exceeding 99%1, and does not cross react with the BCG vaccine.

The T-SPOT.TB test is also less affected by immunosuppression than other TB tests2,3 so is the perfect choice for those living with HIV, or to screen for TB prior to initiation of Biologic treatments.

IGRAs, such as the T-SPOT.TB test have been recommended for use in clinical guidelines for TB testing in over 30 countries worldwide, including the World Health Organization’s List of Essential In Vitro Diagnostics4.

1 Oxford Immunotec. T-SPOT.TB package insert PI-TB-IVD-UK-V3 Abingdon, UK. 2016

2 Huo Z and Peng L. Accuracy of the interferon-γ release assay for the diagnosis of active tuberculosis among HIV-seropositive individuals: a systematic review and meta-analysis. BMC Infectious Diseases 2016;16:350.

3 Wong SH, Gao Q, Kelvin KF et al. Effect of immunosuppressive therapy on interferon γ release assay for latent tuberculosis screening in patients with autoimmune diseases: a systematic review and meta-analysis Thorax 2016;71:64–72

4 World Health Organization: Model List of Essential In Vitro Diagnostics First edition 2018

T-SPOT is a registered trademark of Oxford Immunotec Ltd.