
Easytence®
The biomedical cell product Easytence ® consists of cultured autologous cartilage tissue cells of the patient, cultivated outside the human body (in vitro). The product is intended for the restoration of cartilage tissue damage in the knee joint with an area of up to 10 square centimeters.
Chondrocytes (the cells responsible for cartilage formation), isolated from a biopsy (tissue fragment) of the patient's healthy cartilage, are cultivated in in vitro conditions at a licensed production facility of GENERIUM. The cartilage-like structures formed as a result of processing, with a spheroid architecture, are implanted into the site of the cartilage tissue defect. Chondrocytes fill the defect area with components of hyaline matrix, providing a regenerative effect.
The cell product is produced individually for each patient and is intended exclusively for personalized use, which eliminates the risks of rejection and infection by foreign pathogens. The possibility and appropriateness of using the cartilage defect repair method for each specific patient is determined by the physician, taking into account the patient's complete medical history.
Easytense® is the first and only fully licensed equivalent of the most in-demand cell product for cartilage repair in the knee joint, Spherox/Chondrosphere, in Europe.
The implementation of the cartilage repair method using the biomedical cell product Easytense ® in clinical practice will be carried out in stages across several medical institutions in various regions of the Russian Federation. A list of clinics will be published shortly and will be updated as the methodology is implemented.
Email address for inquiries: izitens@generium.ru
Registration certificate number: BMC №1.
Isolated single cartilage damage of the knee joint of grade III or IV according to the International Cartilage Repair Society (ICRS) classification, with a defect size ranging from 1 to 10 sq. cm in patients aged 18 years and older.